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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA3
All Species:
30.61
Human Site:
T290
Identified Species:
74.81
UniProt:
Q9H227
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H227
NP_001121904.1
469
53696
T290
S
S
R
L
P
E
F
T
E
E
E
K
K
M
I
Chimpanzee
Pan troglodytes
XP_517125
469
53674
T290
S
S
R
L
P
E
F
T
E
E
E
K
K
M
I
Rhesus Macaque
Macaca mulatta
XP_001105060
469
53778
T290
S
S
R
L
P
E
F
T
E
E
E
K
K
M
I
Dog
Lupus familis
XP_545975
469
53689
T290
S
S
R
L
P
E
F
T
E
E
E
K
R
M
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1F9
566
64807
S324
M
S
R
L
P
T
F
S
L
Q
E
K
S
Y
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513443
542
60826
T360
A
S
R
L
P
E
F
T
E
E
E
K
R
M
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087678
499
56923
T293
T
S
R
L
P
E
L
T
E
E
E
K
A
L
I
Zebra Danio
Brachydanio rerio
NP_001018529
475
53419
P297
P
H
F
S
K
D
E
P
S
P
L
G
T
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792769
548
61806
T327
Q
S
R
L
P
E
F
T
D
E
E
K
T
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIW4
490
56058
S308
K
E
F
M
L
Q
N
S
W
D
F
L
G
L
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.6
87.8
N.A.
36.7
N.A.
N.A.
67.3
N.A.
58.3
52.2
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
99.5
98.9
94
N.A.
53
N.A.
N.A.
76.9
N.A.
73.5
69
N.A.
N.A.
N.A.
N.A.
58.9
P-Site Identity:
100
100
100
93.3
N.A.
46.6
N.A.
N.A.
86.6
N.A.
73.3
0
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
66.6
N.A.
N.A.
100
N.A.
86.6
6.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
10
0
0
0
0
10
% D
% Glu:
0
10
0
0
0
70
10
0
60
70
80
0
0
0
0
% E
% Phe:
0
0
20
0
0
0
70
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
80
30
0
0
% K
% Leu:
0
0
0
80
10
0
10
0
10
0
10
10
0
20
10
% L
% Met:
10
0
0
10
0
0
0
0
0
0
0
0
0
60
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
0
0
80
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
80
0
0
0
0
0
0
0
0
0
20
0
0
% R
% Ser:
40
80
0
10
0
0
0
20
10
0
0
0
10
0
0
% S
% Thr:
10
0
0
0
0
10
0
70
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _